The project is organized in the following work packages:
WP1 Project Management, coordinated by ICFO
Financial and administrative management of the project, coordination of the consortium and planning of the schedule and timings.
WP2 Module and platform development, led by ICFO
To develop and construct a set of hardware and software modules for the integration of fNIRS, DCS and EEG in a device with an appropriate head-cap, and todevelop the TinyBrains platform integrating all the modules into a unique device to provide for high-density.
WP3 Ex vivo phantom validation and standardization, led by BioPixS
Test and validation of the TinyBrains platform, providing protocols and phantom-kits for exploitation.
WP4 Pre-clinical studies, coordinated by the FSJD
To carry out research with TinyBrains in a paediatric animal model.
WP5 Clinical studies, coordinated by FSJD
To validate and carry out studies with the system in healthy infants and in infants with severe CHD, and test its performance during the period prior to cardiac surgery and correlate changes in brain oxygen delivery.
WP6 Physiological and pathophysiological characterization and data analysis, coordinated by UPJV
To interpret and analyse the TinyBrains signals by analysing the function/dysfunction of the neurovascular unit (NVU), brain auto-regulation and vascular and neuronal networks, to assess the complex relationship of these measurands to the extent of neuronal injury and its causes.
WP7 Communication and dissemination, led by ICFO
To disseminate and communicate the project results to the networks of the patient organizations, general public and stakeholders, through conferences, scientific manuscripts and specific communication actions.
WP8 Exploitation, coordinated by HemoPhotonics
To exploit the project results through the protection of intellectual property and through further application of the technology for further research even in other patient populations.
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101017113
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